Parameter
| Biomarker | TNF alpha | Full name | Tumor necrosis factor alpha | Molecular Type | Proteins (cytokines) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Inflammation monitoring, prognosis | ||
| Disease | Acute pancreatitis (AP) | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (immunoassay, ELISA) | ||
| Pathobiological Mechanisms | The key factors of early inflammatory response activate the NF-κB pathway, promote the release of pro-inflammatory factors, and aggravate pancreatic and systemic tissue damage | ||||
| Clinical Availability Status | Commonly used in clinical practice (inflammation monitoring) : It is widely used to evaluate the inflammatory activity of AP and to monitor the efficacy of anti-inflammatory treatment | ||||
| Notes and Dynamics | AP is elevated in the early stage and can quickly reflect the activation of inflammation, but its specificity is low, so it needs to be used in combination with other markers | ||||