Parameter
| Biomarker | miR-19a, miR-143, miR-374-5p | Full name | MicroRNA-19a, MicroRNA-143, MicroRNA-374-5p | Molecular Type | Small RNA (miRNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and Prognosis | ||
| Disease | Chronic pancreatitis (CP) | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum, tissue (RNA sequencing, qRT-PCR) | ||
| Pathobiological Mechanisms | It regulates the expression of inflammatory response and fibrosis-related genes, and the abnormal expression occurs in the early stage of CP, earlier than the imaging changes | ||||
| Clinical Availability Status | Cutting-edge research, has set up a file in the queue of small sample verification, distinguish between CP and healthy crowd accuracy is higher | ||||
| Notes and Dynamics | It has tissue specificity and stability, and is expected to become a non-invasive marker for early diagnosis of CP. It is currently being verified in multiple centers | ||||