Parameter
| Biomarker | miR-221, miR-130a, and miR-199a-3p | Full name | MicroRNA-221, MicroRNA-130a, MicroRNA-199a-3p | Molecular Type | Small RNA (miRNA) |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis and condition monitoring | ||
| Disease | Chronic pancreatitis (CP) | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (qRT PCR, chip testing) | ||
| Pathobiological Mechanisms | Regulation of pancreatic stellate cell activation and inflammation-related pathways is significantly abnormal in CP patients, which is related to the degree of fibrosis | ||||
| Clinical Availability Status | Clinical study phase: Expression differences were validated in CP patients for assessing disease severity | ||||
| Notes and Dynamics | Can be used as the CP potential markers of disease monitoring, is expected to be combined with imaging condition assessment accuracy | ||||