Parameter
| Biomarker | β₂-MG | Full name | β₂- microglobulin | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | diagnosis, staging, prognosis | ||
| Disease | Multiple Myeloma (MM) | Disease Subtypes | / | ||
| Organ | Bone marrow, Kidney | Test Sample / Technology Platform | serum | ||
| Pathobiological Mechanisms | Reflecting tumor burden, elevated levels are associated with active tumor cell proliferation and renal function impairment, serving as a core indicator for R-ISS staging. | ||||
| Clinical Availability Status | International Myeloma Working Group、National Comprehensive Cancer Network (IMWG、NCCN) | ||||
| Notes and Dynamics | Combination with albumin, LDH, and high-risk cytogenetics enables precise stratification; β2-MG levels should be corrected in cases of renal insufficiency to avoid overestimation of tumor burden. | ||||