Parameter
| Biomarker | LDH | Full name | lactate dehydrogenase | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | prognosis, disease activity | ||
| Disease | Multiple Myeloma (MM) | Disease Subtypes | / | ||
| Organ | Bone marrow | Test Sample / Technology Platform | serum | ||
| Pathobiological Mechanisms | Reflects the metabolic activity of tumor cells, with elevated levels indicating rapid tumor proliferation and strong invasiveness | ||||
| Clinical Availability Status | R-ISS staging inclusion criteria, routinely applied in clinical practice | ||||
| Notes and Dynamics | Elevated LDH levels are strongly associated with extramedullary lesions and treatment resistance; R-ISS stage III requires either elevated LDH or any high-risk cytogenetic marker; it can predict the risk of relapse after CAR-T therapy. | ||||