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1159

Parameter
Biomarker cPCs Full name Proportion of clonal plasma cells in bone marrow Molecular Type nucleic acid
Molecular Formula Molecular Weight Core Functional Dimensions diagnosis, staging
Disease Multiple Myeloma (MM) Disease Subtypes /
Organ Bone marrow Test Sample / Technology Platform marrow
Pathobiological Mechanisms The proportion of abnormal clonal plasma cells in the bone marrow reflects tumor burden, with higher proportions indicating poorer prognosis.
Clinical Availability Status International Myeloma Working Group (IMWG)
Notes and Dynamics ≥60% of patients require treatment even without end-organ damage; flow cytometry can simultaneously detect surface markers (CD38, CD138, CD56) to improve the accuracy of clonal identification

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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