Parameter
| Biomarker | CTX | Full name | Type II collagen C-terminal peptide | Molecular Type | Collagen degradation products |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Chondrodegradation monitoring and prognosis assessment | ||
| Disease | Osteoarthritis (OA) | Disease Subtypes | / | ||
| Organ | Joint (Cartilage) | Test Sample / Technology Platform | Urine (ELISA, Western blot) | ||
| Pathobiological Mechanisms | Type II collagen is the primary collagen component of cartilage. After degradation, CTX-II is excreted in urine, and elevated levels indicate active cartilage destruction. | ||||
| Clinical Availability Status | Clinically available | ||||
| Notes and Dynamics | The degradation rate of cartilage can be dynamically monitored, and a decrease post-treatment indicates that cartilage destruction has been inhibited. | ||||