Parameter
| Biomarker | MMP-13 | Full name | Serum matrix metalloproteinase-13 | Molecular Type | protease |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Study on the degradation m echanism of c artilage and m onitoring of t herapeutic effect | ||
| Disease | Osteoarthritis (OA) | Disease Subtypes | / | ||
| Organ | Joint (Cartilage) | Test Sample / Technology Platform | Serum (ELISA, immunohistochemistry) | ||
| Pathobiological Mechanisms | Specifically degrades type II collagen, promotes cartilage matrix degradation, and exhibits a positive correlation with the degree of cartilage injury. | ||||
| Clinical Availability Status | Scientific research verification | ||||
| Notes and Dynamics | A novel MMP-13 inhibitor has entered preclinical studies and can be used as an efficacy evaluation index for targeted therapy | ||||