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Parameter
Biomarker IL-6 Full name interleukin-6 in synovial fluid Molecular Type cell factor
Molecular Formula Molecular Weight Core Functional Dimensions inflammatory activity monitoring, progression prediction
Disease Osteoarthritis (OA) Disease Subtypes /
Organ Joint (Synovium) Test Sample / Technology Platform Synovial fluid (ELISA, flow cytometry)
Pathobiological Mechanisms Post-traumatic intra-articular inflammatory response activation, IL-6 promotes the inflammatory cytokine cascade, exacerbating cartilage damage
Clinical Availability Status In research
Notes and Dynamics The level of IL-6 in synovial fluid>10 pg/mL indicates active inflammation, and anti-inflammatory treatment should be intensified to delay the progression of osteoarthritis.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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