Parameter
| Biomarker | anti-CCP | Full name | Serum anti-cyclopeptidylcarbamide antibodies | Molecular Type | autoantibody |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Differential diagnosis, prognosis assessment | ||
| Disease | Osteoarthritis (OA) | Disease Subtypes | / | ||
| Organ | Joint (Cartilage, Bone) | Test Sample / Technology Platform | Serum (ELISA, Western blot) | ||
| Pathobiological Mechanisms | Associated with articular cartilage and bone erosion, a positive result indicates erosive phenotype and elevated risk of bone erosion. | ||||
| Clinical Availability Status | Clinically available | ||||
| Notes and Dynamics | The positive rate is approximately 30%, significantly higher than that in non-erosive osteoarthritis, and can serve as a differential indicator for erosive phenotypes. | ||||