Parameter
| Biomarker | OPG | Full name | Serum osteoprotegerin | Molecular Type | cytokine recepto |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Bone erosion monitoring and prognosis assessment | ||
| Disease | Osteoarthritis (OA) | Disease Subtypes | / | ||
| Organ | Joint (Bone) | Test Sample / Technology Platform | Serum (ELISA, immunohistochemistry) | ||
| Pathobiological Mechanisms | Regulation of osteoclast activity: A decrease in activity level indicates active bone resorption and increased risk of bone erosion. | ||||
| Clinical Availability Status | Scientific research verification | ||||
| Notes and Dynamics | Patients with OPG levels <3 pg/mL exhibit accelerated bone erosion progression and may serve as a reference indicator for bone-protective therapy. | ||||