Parameter
| Biomarker | PGE₂ | Full name | Prostaglandin E2 in synovial fluid | Molecular Type | Lipid medium |
|---|---|---|---|---|---|
| Molecular Formula | C20H32O5 | Molecular Weight | 352.47 Da | Core Functional Dimensions | Inflammatory activity monitoring, research on pain mechanisms |
| Disease | Osteoarthritis (OA) | Disease Subtypes | / | ||
| Organ | Joint (Synovium) | Test Sample / Technology Platform | Synovial fluid (ELISA, high-performance liquid chromatography) | ||
| Pathobiological Mechanisms | Mediating inflammatory pain and cartilage degradation, with a positive correlation between the level and the degree of pain | ||||
| Clinical Availability Status | Research phase | ||||
| Notes and Dynamics | Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the level of PGE₂ in synovial fluid, alleviate pain, and serve as a direct indicator of drug efficacy. | ||||