Parameter
| Biomarker | miR-21 | Full name | microRNA-21 | Molecular Type | microRNA |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, and drug resistance prediction | ||
| Disease | Osteosarcoma (OS) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | serum, tumor tissue (qRT-PCR、RNA-seq) | ||
| Pathobiological Mechanisms | Targeting the PTEN and TGF-β1 pathways to promote tumor proliferation and chemotherapy resistance | ||||
| Clinical Availability Status | Clinical trials in progress | ||||
| Notes and Dynamics | Related to resistance to cisplatin and doxorubicin, it can serve as a target for combination therapy. | ||||