Parameter
| Biomarker | hsa_circ_0001821 | Full name | Homo sa11piens circular RNA 0001821 | Molecular Type | Circular RNA |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Diagnosis, prognosis, and drug resistance prediction | ||
| Disease | Osteosarcoma (OS) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | tumor tissue, serum(qRT-PCR、RNA-seq) | ||
| Pathobiological Mechanisms | As a ceRNA, it binds to miR-205-5p and upregulates oncogenes such as c-FLIP and FOXC2. | ||||
| Clinical Availability Status | Research phase | ||||
| Notes and Dynamics | Eleven studies consistently reported upregulation, which is closely associated with pulmonary metastasis and chemotherapy resistance. | ||||