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1189

Parameter
Biomarker CRYAB Full name Crystallin Alpha B Molecular Type protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis assessment, metastasis prediction
Disease Osteosarcoma (OS) Disease Subtypes /
Organ Bone Test Sample / Technology Platform Tumor tissue (IHC、Westernblot)
Pathobiological Mechanisms Regulation of the MEK/ERK pathway promotes tumor cell migration and lung metastasis
Clinical Availability Status Scientific research verification
Notes and Dynamics Patients with high expression exhibit reduced 5-year OS rate, which can be targeted by miR-491 inhibition

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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