Parameter
| Biomarker | CRYAB | Full name | Crystallin Alpha B | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognosis assessment, metastasis prediction | ||
| Disease | Osteosarcoma (OS) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | Tumor tissue (IHC、Westernblot) | ||
| Pathobiological Mechanisms | Regulation of the MEK/ERK pathway promotes tumor cell migration and lung metastasis | ||||
| Clinical Availability Status | Scientific research verification | ||||
| Notes and Dynamics | Patients with high expression exhibit reduced 5-year OS rate, which can be targeted by miR-491 inhibition | ||||