Parameter
| Biomarker | RB1 def | Full name | RB1 deficiency | Molecular Type | nucleic acid |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognostic assessment, risk stratification | ||
| Disease | Osteosarcoma (OS) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | Tumor tissue (NGS、IHC) | ||
| Pathobiological Mechanisms | Abnormal cell cycle regulation enhances tumor invasiveness and chemotherapy resistance | ||||
| Clinical Availability Status | Research phase | ||||
| Notes and Dynamics | Closely associated with treatment-related OS, the median OS in missing patients was shortened to 2-3 years | ||||