Parameter
| Biomarker | HSP90 | Full name | Heat Shock Protein 90 | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Prognostic assessment, therapeutic targets | ||
| Disease | Osteosarcoma (OS) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | tumor tissue, serum (IHC、ELISA) | ||
| Pathobiological Mechanisms | Stabilize oncogenic protein conformation, promote tumor cell survival and drug resistance | ||||
| Clinical Availability Status | Clinical trial phase | ||||
| Notes and Dynamics | The HSP90 inhibitor 17-AAG has entered Phase I clinical trials and can inhibit OS proliferation. | ||||