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1193

Parameter
Biomarker EPHA2 Full name EPH receptor A2 Molecular Type membranin
Molecular Formula Molecular Weight Core Functional Dimensions Targeted therapy targets, prognostic evaluation
Disease Osteosarcoma (OS) Disease Subtypes /
Organ Bone Test Sample / Technology Platform Tumor tissue、CTCs (FACS、IHC)
Pathobiological Mechanisms Mediates PI3K/Akt and MEK/ERK signaling pathways to promote angiogenesis and metastasis
Clinical Availability Status Preclinical studies are mature
Notes and Dynamics CAR-T targeted therapy has demonstrated efficacy in animal models, capable of eliminating metastatic lesions.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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