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1194

Parameter
Biomarker Exo-hsa_circ_103801 Full name Exosome-derived hsa_circ_103801 Molecular Type Circular RNA
Molecular Formula Molecular Weight Core Functional Dimensions Drug resistance monitoring, recurrence warning
Disease Osteosarcoma (OS) Disease Subtypes /
Organ Bone Test Sample / Technology Platform peripheral blood exosomes (qRT-PCR、RNA-seq)
Pathobiological Mechanisms Transfer of drug-resistant phenotypes, upregulation of ABCB1 and ABCC1 expression
Clinical Availability Status Research phase
Notes and Dynamics Exosomes from cisplatin-resistant cells exhibit high expression and can induce drug resistance in sensitive cells

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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