Parameter
| Biomarker | ERCC1 | Full name | Excision Repair Cross-Complementation Group 1 | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Drug resistance prediction | ||
| Disease | Osteosarcoma (OS) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | Tumor tissue (IHC, qRT-PCR) | ||
| Pathobiological Mechanisms | Participates in DNA damage repair and attenuates the cytotoxicity of chemotherapeutic agents | ||||
| Clinical Availability Status | Research phase | ||||
| Notes and Dynamics | The rate of chemotherapy response decreased by 50% when co-expressed with ABCB1. | ||||