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1197

Parameter
Biomarker lncRNASNHG16 Full name Small nucleolar RNA host gene 16 Molecular Type long noncoding RNA
Molecular Formula Molecular Weight Core Functional Dimensions Drug resistance prediction, regulatory targets
Disease Osteosarcoma (OS) Disease Subtypes /
Organ Bone Test Sample / Technology Platform Tumor tissue (qRT-PCR、RNA-seq)
Pathobiological Mechanisms Adhesion to miR-16 upregulates ATG4B to promote autophagy-mediated drug resistance
Clinical Availability Status Research phase
Notes and Dynamics The sensitivity of OS cells to cisplatin can be restored after knockdown

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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