Parameter
| Biomarker | β-CTX | Full name | Serum β-collagen cross-linked C-terminal peptide | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Bone Resorption Assessment | ||
| Disease | Osteoporosis (OP) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | Serum (Chemiluminescence, ELISA) | ||
| Pathobiological Mechanisms | Type I collagen degradation products during bone resorption specifically reflect osteoclast-mediated bone matrix destruction, with significantly elevated levels in postmenopausal estrogen deficiency. | ||||
| Clinical Availability Status | Widely available | ||||
| Notes and Dynamics | Significantly influenced by diet, blood sampling requires fasting; positively correlated with hip fracture risk, with a 2.3-fold increase in fracture risk when levels exceed 0.5 ng/mL. | ||||