Parameter
| Biomarker | peripheral blood exosomes circRNA_0007059 | Full name | Molecular Type | Circular RNA | |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Regulation of osteocyte differentiation | ||
| Disease | Osteoporosis (OP) | Disease Subtypes | / | ||
| Organ | Bone | Test Sample / Technology Platform | peripheral blood exosomes(qRT-PCR、RNA-seq) | ||
| Pathobiological Mechanisms | As a ceRNA, it binds to miR-378, upregulates BMP-2 expression, and promotes osteogenic differentiation; its level is significantly reduced in exosomes of idiopathic patients. | ||||
| Clinical Availability Status | Research phase | ||||
| Notes and Dynamics | circRNA_0007059 shows promise as a non-invasive biomarker for juvenile osteoporosis | ||||