Parameter
| Biomarker | SAA | Full name | Serum Amyloid A | Molecular Type | protein |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Assessment of early inflammatory activity | ||
| Disease | Rheumatoid Arthritis (RA) | Disease Subtypes | / | ||
| Organ | Joint (Synovium) | Test Sample / Technology Platform | Serum (immunoturbidimetry, latex-enhanced immunoturbidimetry) | ||
| Pathobiological Mechanisms | Regulated by IL-6 and TNF-α, it participates in neutrophil chemotaxis and synovial inflammation amplification, with its level changes occurring earlier than those of CRP. | ||||
| Clinical Availability Status | Clinical Promotion | ||||
| Notes and Dynamics | It demonstrates higher sensitivity than CRP for early inflammatory activity in rheumatoid arthritis (RA); shows good response to conventional disease-modifying anti-rheumatic drugs (DMARDs). | ||||