Parameter
| Biomarker | pDCs | Full name | plasmacytoid dendritic cells | Molecular Type | immunocyte,immunological cell |
|---|---|---|---|---|---|
| Molecular Formula | Molecular Weight | Core Functional Dimensions | Response Prediction to Treatment (TNF-α Inhibitors) | ||
| Disease | Rheumatoid Arthritis (RA) | Disease Subtypes | / | ||
| Organ | Immune system | Test Sample / Technology Platform | Peripheral blood (flow cytometry, HIPC standardized protocol) | ||
| Pathobiological Mechanisms | Participates in the type I interferon response, regulates autoantibody production and immune cell activation, with its peripheral blood proportion positively correlated with the efficacy of TNF-α inhibitors. | ||||
| Clinical Availability Status | Scientific research verification | ||||
| Notes and Dynamics | It is an independent predictor of TNF-α inhibitor efficacy, with a high proportion of patients showing an improvement in treatment response rate by more than 30%; standardized flow panel testing is required to ensure comparability of results. | ||||