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Parameter
Biomarker Tfh cells Full name T follicle helper cells Molecular Type immunocyte,immunological cell
Molecular Formula Molecular Weight Core Functional Dimensions Response Prediction to Treatment (Abazap)
Disease Rheumatoid Arthritis (RA) Disease Subtypes /
Organ Immune system Test Sample / Technology Platform Peripheral blood (flow cytometry, HIPC standardized protocol)
Pathobiological Mechanisms Regulates germinal center formation and autoantibody production, mediates B cell activation, and its peripheral blood proportion is closely associated with the therapeutic response to abacizumab.
Clinical Availability Status Scientific research verification
Notes and Dynamics Independent predictive factors provide a basis for clinical individualized selection of biologics; they should be combined with other immune cell phenotype analyses.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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