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406

Parameter
Biomarker HA Full name Hyaluronic acid Molecular Type Polysaccharides
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis and assistance improve diagnostic accuracy
Disease Pleural Mesothelioma Disease Subtypes /
Organ pleura Test Sample / Technology Platform Pleural effusion (specific technology platform not specified
Pathobiological Mechanisms Promotes the development of multiple cancers, plays a role in the PM-related microenvironment
Clinical Availability Status In the verification stage of the study: the concentration in pleural effusion increased, and the diagnostic efficacy was similar to that of mesothelin
Notes and Dynamics The two-step diagnostic model can be constructed in combination with mesocortin in pleural effusion, which can further improve the diagnostic accuracy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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