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407

Parameter
Biomarker ctDNA Full name Circulating tumors DNA Molecular Type Nucleic acids (DNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Non-invasive diagnosis, clonal evolution monitoring, and drug resistance mechanism exploration
Disease Pleural Mesothelioma Disease Subtypes /
Organ pleura Test Sample / Technology Platform pleura Blood (specific technology platform not specified)
Pathobiological Mechanisms Carrying PM-related gene mutations or methylation abnormalities reflecting tumor genomic characteristics
Clinical Availability Status Cutting-edge research stage: It provides the possibility for non-invasive diagnosis of PM, but has not yet entered clinical application
Notes and Dynamics It can be used for non-invasive diagnosis of PM, dynamic monitoring of tumor clonal evolution, and exploration of drug resistance mechanisms

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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