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Parameter
Biomarker TEC Full name Total Eosinophil Count Molecular Type Cells (eosinophils)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, screening
Disease Asthmae Disease Subtypes /
Organ Airway (trachea, bronchi, bronchioles) Test Sample / Technology Platform Blood, sputum (cell count test)
Pathobiological Mechanisms It is involved in cell adhesion, migration and other processes, and is highly expressed in PM, which is related to the degree of tumor malignancy
Clinical Availability Status Study stage (prognostic value is available, diagnostic value is limited): high accuracy in differentiating PM from healthy people (AUCROC 0.86 to 0.89), but not useful for differentiating PM from benign pleural effusion or other diseases
Notes and Dynamics 1. Low specificity, limiting its diagnostic application; 2. High levels of OPN in PM patients are associated with poor prognosis and have a potential prognostic predictive effect

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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