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415

Parameter
Biomarker FeNO Full name Fractional Exhaled Nitric Oxide Molecular Type gas molecules
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, screening
Disease Asthmae Disease Subtypes /
Organ Airway (trachea, bronchi, bronchioles) Test Sample / Technology Platform Exhaled breath (FeNO detection device)
Pathobiological Mechanisms IL-13 upregulates airway epithelial nitric oxide synthase and promotes nitric oxide production, reflecting Th2 airway inflammation
Clinical Availability Status Clinically available / guideline reference: used to suggest eosinophilic inflammation
Notes and Dynamics Affected by demographic characteristics, smoking, diet and other factors, the level of glucocorticoid tolerance in some patients does not decrease

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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