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Parameter
Biomarker MCP-4 Full name Monocyte Chemoattractant Protein-4 Molecular Type Proteins (chemokines)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, screening
Disease Chronic obstructive pulmonary disease Disease Subtypes /
Organ Lung Test Sample / Technology Platform Bronchial biopsy sample, bronchial irrigation fluid (immunoassay technique)
Pathobiological Mechanisms Patients with COPD (especially in the acute exacerbation phase) have airway inflammation associated with increased production in bronchial tissue and irrigation fluid
Clinical Availability Status Research validation: high diagnostic differentiation value
Notes and Dynamics Combined with eotaxin-3, it shows high AUC values when distinguishing COPD patients from healthy people, and in acute exacerbations from stable phases

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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