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Parameter
Biomarker miR-155、miR-17、miR-181 Full name microRNA-155、microRNA-17、microRNA-181 Molecular Type Nucleic acid(microRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, screening
Disease Chronic obstructive pulmonary disease Disease Subtypes /
Organ Lung Test Sample / Technology Platform Blood (real-time PCR technology)
Pathobiological Mechanisms Abnormal expression profile in COPD patients is involved in disease-related molecular regulation
Clinical Availability Status Research verifies that non-invasive diagnosis has great potential
Notes and Dynamics miR-181 had the highest diagnostic sensitivity, and downregulation of miR-17 reflected remodeling activity, and combined testing enhanced diagnostic and stratification effects

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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