Parameter
| Biomarker | miR-155、miR-17、miR-181 | Full name | microRNA-155、microRNA-17、microRNA-181 | Molecular Type | Nucleic acid(microRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, screening |
| Disease | Chronic obstructive pulmonary disease | Disease Subtypes | / | ||
| Organ | Lung | Test Sample / Technology Platform | Blood (real-time PCR technology) | ||
| Pathobiological Mechanisms | Abnormal expression profile in COPD patients is involved in disease-related molecular regulation | ||||
| Clinical Availability Status | Research verifies that non-invasive diagnosis has great potential | ||||
| Notes and Dynamics | miR-181 had the highest diagnostic sensitivity, and downregulation of miR-17 reflected remodeling activity, and combined testing enhanced diagnostic and stratification effects | ||||