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Parameter
Biomarker MLR Full name Monocyte to lymphocyte ratio Molecular Type Inflammation-related ratio (cellular level)
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, screening
Disease tuberculosis Disease Subtypes /
Organ Lung Test Sample / Technology Platform Blood (routine blood test)
Pathobiological Mechanisms MTB predominantly infects myeloid cells, resulting in an increase in monocytes relative to lymphocytes
Clinical Availability Status Study validation: Shows high sensitivity and specificity in pediatric HIV patients and adults with or without HIV infection
Notes and Dynamics It is more specific for Mycobacterium tuberculosis and is a potential biomarker that needs to be further validated with microbiological markers

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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