Parameter
| Biomarker | Metabolites (ketones, lactic acid, pyruvate, etc) | Full name | Metabolites (ketones, lactic acid, pyruvate, etc) | Molecular Type | Small molecule metabolites |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, differential diagnosis |
| Disease | tuberculosis | Disease Subtypes | / | ||
| Organ | Lung | Test Sample / Technology Platform | Serum, plasma (NMAGRI / NMR, GC-TOFMS, LC-MS) | ||
| Pathobiological Mechanisms | Tuberculosis infection affects the body's metabolic processes, leading to alterations in the expression levels of specific metabolites | ||||
| Clinical Availability Status | Study validation: 30 differential metabolites have been identified, some of which distinguish tuberculosis from other diseases | ||||
| Notes and Dynamics | The expression of 17 types in the serum of tuberculosis patients was significantly higher than that of the control group, and ketone bodies, lactate, and pyruvate could distinguish tuberculosis from community-acquired pneumonia, diabetes, and cancer | ||||