Parameter
| Biomarker | MicroRNAs | Full name | MicroRNAs (has-miR-196b, has-miR-376c) | Molecular Type | Nucleic acid（RNA） |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | tuberculosis | Disease Subtypes | / | ||
| Organ | Lung | Test Sample / Technology Platform | Serum（RNA-seq、RT-PCR） | ||
| Pathobiological Mechanisms | The expression of specific miRNAs is upregulated or downregulated after tuberculosis infection, reflecting changes at the molecular level of the body | ||||
| Clinical Availability Status | Research exploration: Some miRNAs have diagnostic potential verified by RT-PCR, but the sample size is limited | ||||
| Notes and Dynamics | Thirty differentially expressing miRNAs (24 up-regulated and 6 down-regulated) have been identified, and the lack of large-sample validation cohorts limits global applicability | ||||