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605

Parameter
Biomarker NfL Full name Neurofilament Light Chain Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Monitoring, Prognosis
Disease Schizophrenia Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma/Cerebrospinal Fluid (SIMOA)
Pathobiological Mechanisms A marker of neuronal axonal injury, reflecting the neurodegenerative process.
Clinical Availability Status Under clinical validation
Notes and Dynamics Positively correlated with the degree of cognitive impairment, can assess disease activity.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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