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451

Parameter
Biomarker EGFR Full name Epidermal Growth Factor Receptor Molecular Type Nucleic acid(DNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Targeted therapy guidance
Disease Non-Small Cell Lung Cancer Disease Subtypes /
Organ Lung Test Sample / Technology Platform Tissue / Blood (Genetic Testing)
Pathobiological Mechanisms Driver gene mutations, exon 19 deletion, exon 21 L858R point mutation, and other types enhance TKIs sensitivity
Clinical Availability Status Clinically available (targeted therapy screening)
Notes and Dynamics The incidence of lung adenocarcinoma in Asia is about 50% and is a core screening marker for targeted therapy

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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