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452

Parameter
Biomarker ALK Full name Anaplastic Lymphoma Kinase Molecular Type Nucleic acid(DNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Targeted therapy guidance
Disease Non-Small Cell Lung Cancer Disease Subtypes /
Organ Lung Test Sample / Technology Platform Tissue / Blood (Genetic Testing)
Pathobiological Mechanisms Fusion genes cause tumorigenesis and can be specifically inhibited by ALK inhibitors
Clinical Availability Status Clinically available (targeted therapy screening)
Notes and Dynamics The incidence is 3% to 7%, and it is more common in young, non-smokers, or light smokers with lung adenocarcinoma

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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