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453

Parameter
Biomarker ROS1 Full name c-ros Oncogene 1 Molecular Type Nucleic acid(DNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Targeted therapy guidance
Disease Non-Small Cell Lung Cancer Disease Subtypes /
Organ Lung Test Sample / Technology Platform Tissue / Blood (Genetic Testing)
Pathobiological Mechanisms Fusion genes drive tumors that are sensitive to ROS1 inhibitors
Clinical Availability Status Clinically available (targeted therapy screening)
Notes and Dynamics The incidence is 1%-2%, similar to the clinical features of ALK fusion, and the inhibitor effect is significant

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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