Parameter
| Biomarker | Mismatch Negativity | Full name | Neurophysiological Indicator | Molecular Type | / |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | Brain | Core Functional Dimensions | Electroencephalogram (EEG, Time-Frequency Analysis) |
| Disease | Schizophrenia | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | NMDAR functional abnormalities lead to early auditory processing disorders, reflecting excitation-inhibition imbalance. | ||
| Pathobiological Mechanisms | NMDAR functional abnormalities lead to early auditory processing disorders, reflecting excitation-inhibition imbalance. | ||||
| Clinical Availability Status | Research validation stage | ||||
| Notes and Dynamics | Sensitive to D-serine and 5-HT3R antagonist treatment, can predict target engagement. | ||||