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454

Parameter
Biomarker NSE Full name Neuron-specific enolase Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, screening, efficacy monitoring, and early warning of recurrence
Disease Small Cell Lung Cancer Disease Subtypes /
Organ Lung Test Sample / Technology Platform Serum (specific technology platform not specified)
Pathobiological Mechanisms SCLC cells have neuroendocrine properties and secrete NSE, a key enzyme in the glycolytic pathway, in large quantities
Clinical Availability Status Clinical application: Commonly used serum markers, which need to be combined with clinical symptoms and imaging examinations
Notes and Dynamics It may be elevated in neuroblastoma, medullary thyroid carcinoma, pneumonia, meningitis and other diseases, and there are interfering factors

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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