Parameter
| Biomarker | ProGRP | Full name | Gastrin-releasing peptide precursor | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, screening, disease progression monitoring, recurrence early warning |
| Disease | Small Cell Lung Cancer | Disease Subtypes | / | ||
| Organ | Lung | Test Sample / Technology Platform | Serum (specific technology platform not specified) | ||
| Pathobiological Mechanisms | ProGRP is a precursor to gastrin-releasing peptide (GRP), which promotes tumor cell proliferation and angiogenesis, and is highly expressed in the serum of SCLC patients | ||||
| Clinical Availability Status | Clinical application: Differential diagnosis performance is better than NSE, potential early screening marker | ||||
| Notes and Dynamics | Elevations in early SCLC precede radiographic abnormalities and have high specificity | ||||