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609

Parameter
Biomarker IL-1β Full name Interleukin 1β Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis, Diagnosis
Disease Schizophrenia Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma/Cerebrospinal Fluid (ELISA)
Pathobiological Mechanisms Activates the inflammasome pathway, promotes neuronal apoptosis, and interferes with GABAergic transmission.
Clinical Availability Status Under clinical validation
Notes and Dynamics CSF levels in elderly patients are positively correlated with cognitive decline.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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