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Parameter
Biomarker PD-L1 Full name Programmed Death Ligand 1 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prediction of immunotherapy efficacy
Disease Small Cell Lung Cancer Disease Subtypes /
Organ Lung Test Sample / Technology Platform Tumor tissue (specific technology platform not specified)
Pathobiological Mechanisms PD-L1 binds to PD-1 on the surface of T cells and inhibits immune cell killing of tumor cells
Clinical Availability Status Study validation: predictive markers of immunotherapy efficacy
Notes and Dynamics The expression heterogeneity in the tumor tissues of SCLC patients was strong, with a positive expression rate of 10%-30%, and the detection platform and cutoff value standards were not unified

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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