Parameter
| Biomarker | MDR1 | Full name | Multidrug Resistance Gene | Molecular Type | Nucleic acids (DNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Chemotherapy efficacy prediction and treatment plan guidance |
| Disease | Non-Small Cell Lung Cancer | Disease Subtypes | / | ||
| Organ | Lung | Test Sample / Technology Platform | Not specified (specific technology platform not specified) | ||
| Pathobiological Mechanisms | The P-glycoprotein (P-gp) encoded by the MDR1 gene can expel chemotherapy drugs from the cell, leading to multidrug resistance in tumor cells | ||||
| Clinical Availability Status | Study validation: Used to predict chemotherapy efficacy | ||||
| Notes and Dynamics | High expression before chemotherapy suggests a high risk of resistance to chemotherapy drugs such as etoposide and paclitaxel, and poor efficacy | ||||