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Parameter
Biomarker Melatonin Full name Melatonin Molecular Type Hormone
Molecular Formula C13H16N2O2 Molecular Weight 232.28 g/mol Core Functional Dimensions Monitoring, Prognosis
Disease Schizophrenia Disease Subtypes /
Organ Brain Test Sample / Technology Platform Saliva/Plasma (ELISA, LC-MS/MS)
Pathobiological Mechanisms Circadian rhythm disturbance; decreased secretion weakens anti-inflammatory and neuroprotective effects.
Clinical Availability Status Research Stage
Notes and Dynamics Decreased nighttime levels are associated with comorbid insomnia; exogenous supplementation can improve sleep quality.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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