Parameter
| Biomarker | TRAF7 Mut | Full name | TRAF7 Gene Mutation | Molecular Type | Gene Mutation |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prognosis |
| Disease | Meningioma | Disease Subtypes | / | ||
| Organ | Brain, Meninges | Test Sample / Technology Platform | Tumor Tissue (NGS, PCR) | ||
| Pathobiological Mechanisms | Encodes an E3 ubiquitin ligase, often co-mutated with AKT1/KLF4, regulates the NF-κB pathway, and is associated with a benign phenotype. | ||||
| Clinical Availability Status | Under Clinical Validation | ||||
| Notes and Dynamics | Mostly found in WHO Grade I meningiomas, 5-year survival rate ≥90%, and can be used as a biomarker for distinguishing benign subtypes. | ||||