Parameter
| Biomarker | GFAP | Full name | Glial Fibrillary Acidic Protein | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Susceptibility, Early Diagnosis |
| Disease | Alzheimer's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma (SIMOA) | ||
| Pathobiological Mechanisms | A marker of astrocyte activation. In AD, it may be activated early in response to Aβ pathology. | ||||
| Clinical Availability Status | Cutting-edge research: A large body of evidence indicates changes in the pre-symptomatic stage, making it a highly promising risk warning biomarker. | ||||
| Notes and Dynamics | Highly correlated with Aβ pathology, may reflect changes in the brain earlier than p-tau. | ||||