Parameter
| Biomarker | Syt-1 | Full name | Synaptotagmin-1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | Alzheimer's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF (ELISA, Western Blot) | ||
| Pathobiological Mechanisms | A synaptic vesicle membrane protein that regulates neurotransmitter release, released into CSF after synaptic injury. | ||||
| Clinical Availability Status | Research exploration: CSF levels are significantly elevated in AD dementia patients, distinguishing AD from other dementias. | ||||
| Notes and Dynamics | Correlated with reduced synaptic density, not yet used in routine clinical testing. | ||||