Parameter
| Biomarker | Syp | Full name | Synaptophysin | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | Alzheimer's Disease | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF (ELISA, Flow Cytometry) | ||
| Pathobiological Mechanisms | An integral membrane protein of synaptic vesicles that maintains neurotransmitter release; CSF levels increase after synaptic loss. | ||||
| Clinical Availability Status | Research exploration: The proportion of microvesicles containing synaptophysin in CSF of AD patients is elevated. | ||||
| Notes and Dynamics | Related to the AD immune microenvironment, can assist in judging the degree of synaptic injury. | ||||